One of the essential elements of the sleep mechanism is melatonin, a hormone naturally produced by the pineal gland when it’s dark. By secreting melatonin, the pineal gland informs the brain that it’s dark and that it’s a good time to sleep.

Melatonin synthesis begins in the absence of light, peaking between 2 and 4 a.m., then decreases during the second half of the night in preparation for wakefulness. In some individuals, this message no longer functions correctly, leading to difficulties falling asleep or shifting sleep times.

Chronobiane Immédiat is a dietary supplement in the form of a sublingual spray (sprayed under the tongue) containing melatonin and hawthorn extract.

Resynchronization” can be achieved by boosting melatonin intake with 1 or 2 sprays of Chronobiane Immédiat at bedtime or on waking (1 spray provides 0.5 mg melatonin).